Apolipoprotein E includes a binding site which is recognized by several amyloidogenic polypeptides
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منابع مشابه
Apolipoprotein E includes a binding site which is recognized by several amyloidogenic polypeptides.
Inheritance of the apolipoprotein E (apoE) epsilon 4 allele is a risk factor for late-onset Alzheimer's disease (AD). Biochemically apoE is present in AD plaques and neurofibrillary tangles of the AD brain. There is a high avidity and specific binding of apoE and the amyloid beta-peptide (A beta). In addition to AD apoE is also present in many other cerebral and systemic amyloidoses, Down's syn...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2000
ISSN: 0264-6021
DOI: 10.1042/0264-6021:3490077